msa: an R package for multiple sequence alignment

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msa: an R package for multiple sequence alignment

UNLABELLED Although the R platform and the add-on packages of the Bioconductor project are widely used in bioinformatics, the standard task of multiple sequence alignment has been neglected so far. The msa package, for the first time, provides a unified R interface to the popular multiple sequence alignment algorithms ClustalW, ClustalOmega and MUSCLE. The package requires no additional softwar...

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Multiple sequence alignment (MSA) is an NP-complete and important problem in bioinformatics. In this paper, we have proposed iterative alignment method using a Genetic Algorithm for Multiple Sequence Alignment, named TSGA-MSA. The steps in this algorithm are discussed in details and its performances on a set of benchmark datasets from the BAliBase 2. 0 are analysed. The experimental results, th...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2015

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btv494